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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee1fc7c95a193f41bd2fee31e341c6671d73d1f7fc9e4bddd1dfa83c90acf784' 
  AND token = 'Acmqx/731C8Y7Pg1k2yat7O5Y7crXRg2GAIs+A3rkZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}