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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a51b295b74d58f8b17b1cff13d7b52279450325a7bde56a5fc662f94db7e04' 
  AND token = 'DvWiUAVF6r9OEBq9+oCpNb/a+pIp9rUOXA7WT9gOyxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}