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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5184f7579e433dbebfac2313290aa22d75621ef9c0c658e00be3e9b14d914e42' 
  AND token = '0rHpSkkwZO5SFHcq1i5YKeFkD87x+zwIO0rVeXw8V8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}