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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53461b747aa0df4f6bb5ad640796a45099c7e38e1aa8f60eca38e33aee55d5a9' 
  AND token = 'g1q7RCkpgb0rC8uNIp2doHm/5f1tjKC9EeRdRqfGxpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}