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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc339011b74a989fdb7a7a2e0c98eed8f7ffb0c7e5644bd51e68969661564413' 
  AND token = 'DmoPGdisLaLJgpdUN2yqITxC9DpxKOFcbuy5hUejOyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}