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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe376d5586cefa0d1e70d0829fea5e49b435c030d5e12cd2e1f5a7858dbafe1' 
  AND token = 'nbSRPpwG1zuXZLvOkZPB0ur0V2YzDGMm9ufgyd0pZw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}