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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436d557ca15c2eaa7c2df2a3168ecd74a532bfb4282af8e9da5b078a0c75ee89' 
  AND token = 'zSykZi9n38vzdJIldDrFIrGIaUCR1bSmjGI1TzYviTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}