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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa38b399e5bc4e1a87cfc7d44542414a5579cdaf5ce088e8630a2988772e704' 
  AND token = 'HxeSw11IYjda4kr/Ch3NNdc+x8kkB3mT3qUWQ1LiuyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}