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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75eaa25de88138162e5198e1d689e6d1c259bfe6117772686934e93e6c5d5a93' 
  AND token = '/ENdT2+JtEH+2BMwMv3q8L2kZu+zAJSUQ/zarD4DhDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}