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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343af91e762cd4a0bb291442abfb5ac9d34fb505f8e354e9fefb8de1e75dafcc' 
  AND token = 'LerOTKIvpU2NJNXqbnDpDRRh24qF/yKT1BcIFBarvwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}