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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22176950acca720b8e50ec55a73b7e7f80e53eb04a38500302428e6f7563f9cc' 
  AND token = 'KxNr7YgbggdmhymYb0FUp/HscpACS6Xe0ezkRIDhEAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}