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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ca3adcf0a059c83a4afe59bc21ce85bead514efc276f0715d18fe644503bb1' 
  AND token = 'Y6vINp4XVkv2/Og/c8fHILb8Ry3mAP9KjnbMJ/iX7xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}