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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9161896264ec60b2b4dd3492b416bf95b528325643c8ea749c10d3876ec81098' 
  AND token = '4UBlP4+RhQUwmbB0pSjFbPAfSQIs/4p8BI8IoBg1gG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}