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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0444b4719143ef60ca1ae06547a1cac98bc6bfee3d8274661f0d2083eb319462' 
  AND token = 'UDpIsmIQJLe3nLbwP3EXAx2Inf4/SYtcC3ztD8BAStY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}