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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288c1dac409e0f84b10fc482cf107e761523db39428c9dc081018e4672fcad3c' 
  AND token = '7r6xGuIDSyI2CXP+bZCncxLiv4pczXxL2WyVjUJ9p9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}