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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3538c774c8d348d0d99a42ebb3c9827893d9eb969b51a1c3d7480c19ada356cd' 
  AND token = 'w9fF6XdqpbP5v4+JQ1AoRbZh8IO/ek6wJScxv0Now6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}