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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4afc25bac86bdfe40551a4c98bdbc86cfc57adb657091a2b36cd01c67b527b3' 
  AND token = 'WsGOPpAaY6XZuRlGmULSGidCcgL7VgTD1mJ7dwH6Fg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}