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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7dff07b07c7d8c705be77d2c93e5db91a3fde6f6b2be3febd1a26250458762' 
  AND token = 'lB+1VE2SeM4e/voJMtANtyPQXkVxkZ/sS1RuwTguZXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}