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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290ce3abcdde397c68fa713113b7a2d51de35683d9e04e257b7ba371a0864100' 
  AND token = 'sFvnHe6PZcVhOUOx/FAE61p1GRBryLYFcEBrUb1+B3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}