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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7be66892473bffa7b9c3afb9a83bd0c5ea193eabbdb51b497464075214b49b' 
  AND token = '9zkIiFsIJ6kwtCI2wrO+bU6vX6XpCu1q5rKiuPRCeZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}