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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec75cfcaea4c08f6e6347a7bf7260274ce504768ab66922fa540e9c8e0a9789' 
  AND token = '4ZOPXxMpI0tfF1B+CDWJlpHANuazyvRJ5c9nHo138KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}