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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2228cd75500763369fc6415645e7150b67d0db22ae7c3f5048e20e55435283bd' 
  AND token = 'M5Acpthk+uf8DXDhXX/Kbd4Yx0YdrRhJYpfcx7Sw2ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}