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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe557d49d51426c80602684e2787cad00aa4f9cb575bc971b53ac14439634c1' 
  AND token = '/Ol6A7gK2ERCgsLalR1B+8e4EcYJClU/hWAzRKFNg8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}