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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0ab662ecce58d4e57b19ebfcb67d10c7288182731aba3f1f221af6d0d5c1a3' 
  AND token = 'aVrC9OpC7p7ynNq+ViPC3z0bT5Yr+7iZlnfbdxLnlOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}