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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a09610007ce34c7cad63cf595e5bf066353c6cb6b188c65a9e75d12a8e69e2f' 
  AND token = '0N04JQ/IJXAwfUAME33miRAht35O/9qOrVhXU/E3/to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}