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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc926a181d56bcc753afa7619255eddf374897b685472f2539c6d7e93d90718' 
  AND token = 'gwPRaiNrk31Sk9sR/5lWOshqfVuL+oI+361Sx7qdDWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}