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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10b23d2f0d0716ba1efe77e10050d711462e21ff1b27cc658f3406eaa1da510' 
  AND token = 'Ry1IiP4zRYrcPXN0Jdpf5nzF7SsVtUlmnSrUNdgZUZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}