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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486abb4e62dfed959df854dc548b0f2903b29eb003752885d6b166a4b554f03b' 
  AND token = 'HQvgTL1lQpabAIxrRWbM2h/iFTuXk8PkeKC9cY5exEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}