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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f29c991b9d97ce0e08f72f381e1f32b7bc867c0a727dabda41b885d5c49e45' 
  AND token = '7WEtEvOWP0e7vB7A3OjyFXDzsUQvFBmVYiD768K4N9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}