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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a48be6eff28ce23363c5030f5987eec6aabcf1ada3e7f2a3db2bdda18f7d978' 
  AND token = 'wUxQMn4eC0A8w9VF+CQxlwtd3mZB6ayo2UAuRK9jfrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}