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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fd9d5111778bd8bed7b9c29f9fd1039122d9237705cd06ea6441e19bf2139f' 
  AND token = 'm6H/Y6aDGbdLioN8b6A3lwUnbqxRtphy8CA4BTsyEo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}