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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33578e46144c1354e069b7238c84bb634cef6132264f63b47e72289e467c6740' 
  AND token = '6MxWRknNQbl+OuIQU3/RdoYy+bAmiRRa+jmD02T+9aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}