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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65b225af84310d842227cd19c90e56312b5e7f18e0ac2a75f102bee27a02d97' 
  AND token = 'u7kf0Eql/hLvvgB7Kfxu1Qtf5qQyR4T5g27vBl25PH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}