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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae764b3d39e08fa05501a299ce94ca081f324e4b2d97ae34a35ca3d99c1d65c' 
  AND token = 'zCIXZCWI+k82NBqg+wPAcbIUO2+Pipr+8CeMSi8sj0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}