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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8377f9eadd690560ae740354ad7d27aae1804e5d0d0511d1b7ec705049ccba' 
  AND token = 'gP/nk+K+R0ETY6gvFbD1cID4BlmZgQCmBIjAoHzFlOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}