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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef8f57904b28d3c285aceefce3597c7e3179e4adcbe681d0d0e9d3a0e641998' 
  AND token = 'OCIILGSHKmo9JU9XCg4l6bDenKHhw11J2TmlQPQNwzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}