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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53f66580f086ac350f67f7bead4c72fa586d5f28f0f31f7c512bdc4c8ebf7d2' 
  AND token = 'RPOc/c43V/Doo71ylR4YXGe5eA2mhGMTMdpd0D52O5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}