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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9220ccbc2c1396c45a23cde1ba39d2b82b5d878bf41062a59306c1180f8c473' 
  AND token = 'XLREXAB0iUu7E9d6Ptdba2vQ0p7P2OfAKeZX5PnFZGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}