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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e561398140f0d1e846509774e5ba2ce4f9a78bd140598a582d9691bfc0da86f' 
  AND token = 'asDVyh01dP5Ds/evc6fTc2QbxR/A1k5l+3wIyps5wBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}