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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8df528b39293c7a3fd5e1f2d0f1ef430d9709fdd297e05aee8d78d1aca945f' 
  AND token = 'r+4hGMnL4zA8jfxsKMy5fhXlR6SwGxmfiFIH9Q4qOVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}