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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c23e6f146669a9fc25c6202945cc2c99126f3c34c2f6d03a389754b08561bd05' 
  AND token = 'U4IkhSV/IzaMGW05G2VvI2SYG+wvmJEg4nEo4Zy3+eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}