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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d05362cd7e72053f3be15370fc30ff6b810de07894c1d7071b9be1e0725802' 
  AND token = '9JfDS8sIrQ8lqSOhhEbRCr3bZZk+T4bqeXg3xT1e47Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}