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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d48c388ebda21774cf73cabe065eb2815253c04f800f07b2a6dd0153646589' 
  AND token = 'wpo3SroUyRMzAmVDBPcS00E8QKJswX21OeKy6Sfx+JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}