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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8390ee6321b432a7d8e7680d1d5cf47b44480d034fac0ff7b0e4098e1c82900' 
  AND token = 'aHZh/F3wwHivxt1K5mca3zQeSOLJuc7rMUHrAjVpQm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}