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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3280e7fa95bf2c0e2b5cb254f0783548c2de4097212a67c38b5c4eb7a49f6a61' 
  AND token = 'A8I1KxehwDzN5bwYApFIBqyvZn0re/9TfrPAf4fuwqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}