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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b505ba88076e59cec1f24dc542f530994ba2afca35f9a66ffb29bb57b1c565f' 
  AND token = '+AYhWGCX6dqphE+yY1lDWNDYaijl6w7NWt5CVkIiiCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}