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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0c3f38add86f59b06391ec778e7702297f8ad6bf2055e85f49523e2caf3665' 
  AND token = '8P7w7/XuTvmo5A10um/SK6EX0wUbNf17IFoGwfm+ze8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}