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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5046d2bb2b296229bc4f3a98c0ef01940157b4405e88ac8d44adca04e40458d2' 
  AND token = '59tfR7tMFJqIo+Gpe6SZmN4ZBlT8TKVNYq80ZAzVqKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}