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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3433a20f74697116197d71f8380cd0738397a9cdefc4d4fa34f41965fe4c13' 
  AND token = '5h+tUkaPzO8fIvtfOOUE3pPaBMGS+nRMrCEXL2jD2Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}