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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da45b868f756bd6281c256e9a22ef6164ab9a0efa0b399c0a1e6e7d179391c87' 
  AND token = 'o4qEVbP7qF4DRaXgOx3KO4imOwMg3gr2yPeo7RB9wec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}